The quest for longevity: 10 European startups shaping and defying the future of ageing

Nov 20, 2025 - 17:00
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The quest for longevity: 10 European startups shaping and defying the future of ageing

Since the dawn of civilisation, humanity has been captivated by the idea of eternal youth. From ancient myths of the Fountain of Youth to modern-day research into longevity, the quest to defy ageing and preserve vitality has driven much of our progress. It is a pursuit that transcends cultures and generations, a constant aspiration to remain youthful, energetic, and healthy well into old age.

Technological and scientific advancements might have propelled us closer to this dream. Breakthroughs in genetic research, personalised medicine, and health monitoring are making it possible to track, understand, and intervene in the biological processes of ageing. From gene therapies that target the root causes of ageing to AI-driven platforms that optimise health, the tools we now have at our disposal offer unprecedented insights into how we can live healthier for longer.

While we may not have found the secret to eternal youth just yet, there are numerous startups pushing the boundaries of what’s possible in the fight against ageing. In this article, we highlight 10 startups that are revolutionising the pursuit of longevity and vitality, not only enhancing the way we age but also reshaping our understanding of what it means to live a long, healthy life.

360-me

Based in London, 360Me is an AI-powered longevity platform that transforms lab results, wearable data, and biomarkers into personalised health insights. By integrating large-scale research such as the UK Biobank, the platform delivers tailored daily recommendations via its consumer app, helping people live longer, healthier lives.

Founded in 2021, their hybrid model combines deep healthtech infrastructure, including the 360Me SDK (currently in development), with a direct-to-consumer longevity experience. To date, they have raised €1.78 million in funding. The company’s focus on data-driven, science-backed solutions aims to provide individuals with actionable insights that can enhance healthspan and promote longevity.

Aware

Based in Berlin, Aware helps individuals monitor their health with personalised blood tests. By using its mobile app, users can measure over 70 biomarkers, including cholesterol, insulin, and vitamin levels, gaining detailed insights into their overall health. This empowers users to make data-driven decisions about their lifestyle, track changes over time, and optimise their health. The results are available directly in the app within two working days, allowing users to act quickly on the findings.

Founded in 2021, Aware has raised €13.6 million in funding. The company offers a wide variety of health packages, targeting different areas such as long-term health, immune health, and sport-specific tests. Their mission is to make health monitoring accessible and actionable, helping individuals take control of their well-being with data and personalised recommendations.

Avea

Based in Zug, Avea offers a range of scientifically-formulated dietary supplements aimed at slowing the signs of ageing and supporting overall health. Avea’s products, such as the Collagen Activator and Biomind, combine cutting-edge ingredients like NMN and probiotics to enhance energy, digestion, skin health, and more. Their approach is rooted in longevity science, with each product crafted using bioavailable plant extracts and compounds for maximum effectiveness.

Founded in 2021, they have raised €5.83 million in funding. Avea’s focus on high-quality, science-backed solutions is reflected in its expert-led formulations, developed in collaboration with top scientists and medical professionals. With more than 30,000 satisfied customers, Avea aims to be a trusted partner on your journey to longevity, offering products designed to support energy, gut health, skin rejuvenation, and more.

CARE

Based in Winterthur, Switzerland, CARE offers modern, comprehensive health check-ups to help individuals take control of their well-being. With the ability to test over 100 biomarkers in just 20 minutes, they provide detailed insights into key health factors such as metabolic function, heart health, and vitamin levels. After each test, users receive personalised recommendations from certified Swiss doctors via the CARE app, helping them track and optimise their health over time.

Founded in 2022, CARE has quickly built a community of over 4,000 members. The company raised €5.6 million in funding and focuses on providing accessible and high-quality preventive healthcare. With locations across Switzerland, CARE integrates cutting-edge medical technology with a holistic approach to wellness, making it easier for individuals to monitor their health and increase their longevity.

Genflow-Biosciences
Dr Eric Leire, CEO of Genflow Biosciences. Photo by Thomas De Boever

Based in the UK, Genflow Biosciences is a biotechnology company focused on developing novel therapeutics aimed at halting or slowing the ageing process in both humans and dogs. The company’s lead compound, GF-1002, utilises a centenarian variant of the SIRT6 gene, which has shown promising preclinical results. This gene is associated with longevity, and by introducing it into the body, Genflow aims to extend healthspan and lifespan, potentially reducing the societal and economic challenges posed by an ageing population.

Founded in 2020, Genflow has secured €8.42 million in funding. The company is driven by a team with decades of experience in the pharmaceutical and biotech sectors and collaborates with renowned research centres and longevity funds. Its mission is to revolutionise the fight against ageing with breakthrough therapies, including GF-1002, which has the potential to change how we approach age-related diseases and the ageing process itself.

Genflow-Biosciences

Based in Newcastle, GlycanAge is revolutionising how we measure biological age and chronic inflammation. Their advanced biological age test, grounded in over 30 years of research, uses glycans – molecular markers of inflammation – to provide precise insights into how lifestyle, stress, and medical interventions impact ageing. GlycanAge helps individuals and healthcare providers track inflammaging, a key contributor to many age-related diseases, including heart disease, diabetes, and dementia.

Founded in 2020, GlycanAge has raised €4.58 million in funding and analysed over 300,000 samples and published over 350 scientific papers. The company’s approach to ageing is backed by a world-class advisory board of scientists, clinicians, and longevity experts. GlycanAge empowers users to track their biological age and inflammation levels, helping them make data-driven decisions to slow down the ageing process and improve long-term health.

Mitra-bio

Based in London, Mitra Bio is transforming the way skin health is assessed by replacing invasive biopsies with non-invasive skin testing. Their advanced next-generation sequencing technology analyses epigenetics, allowing for precise insights into biological ageing, UV damage, and the effectiveness of skin therapies. By measuring DNA methylation markers, Mitra Bio helps track the skin’s ageing process and supports the development of targeted, precision dermatological treatments.

Founded in 2020, Mitra Bio has raised €2.94 million in funding. The company is trusted by global brands to expedite clinical trials and product discovery, using its proprietary tape-stripping technique for collecting biological material. With a focus on advancing age-reversal technologies and precision dermatology, Mitra Bio is leading the charge in non-invasive skin epigenetics testing.

RxLongevity

Based in Spain, RxLongevity focuses on extending the healthspan of individuals aged 60 and above. The company offers an AI-powered chronic pain and longevity plan that combines exercise, rehabilitation, workshops, and educational content to manage pain and improve overall health. They track progress using AI tools, gait analysis, and biomarker measurements to personalise treatment and guide users toward better functional, metabolic, emotional, and cognitive health.

Founded in 2020, RxLongevity has raised €2.83 million in funding. Their platform provides seniors with a holistic approach to ageing, including live group sessions with healthcare specialists, personalised fitness plans, and a strong focus on preventing common age-related diseases.

Tomorrow-bio

Based in Berlin, Tomorrow.bio is pioneering the field of cryonics with its mission to make biostasis more accessible, safer, and affordable. Founded in 2020, Tomorrow.bio offers cryopreservation services, preserving individuals after death in liquid nitrogen with the hope that future medical advancements will allow for revival. The company also provides the only whole-body field cryoprotection procedure, developed in-house to ensure the preservation process is as effective and damage-free as possible.

Founded in 2020, Tomorrow.bio has raised €5 million committed to pushing the boundaries of medical science, with a strong focus on research, technology, and ethical practices. The company operates a purpose-built, Swiss-based facility for patient storage, offering long-term security and stability. It is the first provider in Europe to offer cryopreservation services, and it has expanded its reach to the United States, allowing Americans to access its groundbreaking cryonics services.

zoi-tech

Based in Paris, Zoī is a health and wellness company that helps individuals optimise their health through medical assessments and personalised action plans. Zoī’s check-up process includes advanced medical imaging, laboratory tests, and functional examinations to provide a holistic view of a person’s health. Based on the results, they create a tailored action plan, called the Life Journal, which provides daily recommendations to improve energy, nutrition, physical performance, and stress management.

Founded in 2021, Zoī has raised €20 million, aiming to transform how people approach long-term health optimisation. Their services are designed and developed by a committee of doctors and researchers, ensuring scientific accuracy and consistency, helping individuals anticipate chronic health risks and improve their quality of life through ongoing monitoring and a personalised approach.

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